Methods: We assessed vitamin D and K status by measuring circulating 25-hydroxyvitamin D (25(OH)D) and desphospho-uncarboxylated Matrix Gla-Protein (dp-ucMGP), respectively in 135 hospitalized COVID-19 patients in relation to inflammatory response, elastic fiber degradation and clinical outcomes. Both vitamin D and K have been proposed as potential modulators of this process. 5Department of Biochemistry, Cardiovascular Research Institute Maastricht, University of Maastricht, Maastricht, Netherlandsīackground: Pathology during COVID-19 infection arises partly from an excessive inflammatory response with a key role for interleukin (IL)-6.4Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, Netherlands.3Department of Clinical Chemistry, Canisius-Wilhelmina Hospital, Nijmegen, Netherlands. ![]()
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